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KMID : 0385919940050010026
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Journal of the Korean Society of Emergency Medicine
1994 Volume.5 No. 1 p.26 ~ p.33
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Comparison of Hemodynamic Effects of Intraosseous and Central Venous Routes of Pentaspan(10% Pentastarch) for Resuscitation of Hemorrhagic Shock in a Swine Model
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이원재
박규남/황주일/임근우/김세경
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Abstract
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Venous access remains often as a clinical problem for pediatric patients in hemorrhagic shock state. This study compares resuscitation with PENTASPAN(10% pentastarch) by central venous and intraosseous route in a hemorrhagic shock model. The
swines
were
bled to a mean arterial pressure of 30mmHg. This state of shock was sustained for 30 minutes. Resuscitation was performed with Pentaspan infused at 50mL/min by a manual pressure. The hemodynamic response to Pentaspan resuscitation was comparable
in
both
group. There was no significant difference in mean arterial prossure, heart rate, cardiac output, pulmonary capillary wedge pressure, pulmonary artery pressure, arterial oxygen saturation, and mixed venous oxygen saturation.
For fixed rate infusion, intraosseous resuscitation with Pentaspan is as effective as that infused by contral venous route in improving hemorrhagic shock state.
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KEYWORD
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